THE ULTIMATE GUIDE TO GENETIC METHYLATION TEST GARY BREAKA

therapy with sodium bisulfite deaminates unmethylated cytosine to uracil, Whilst 5mC is just not impacted. Subsequent PCR amplification will replace the uracils by thymines. Reads from NGS libraries produced in parallel with and without bisulfite remedy are mapped onto reference genomes and also the contrasting C/T positions in between the librarie